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Translational Research and Population Health Management

Translational Research and Population Health Management

Translational Research and Population Health Management

TOPIC: Benchmark – Part B: Literature Review

In Part A, you described the population and quality initiative related to your PICOT (Population/Problem, Intervention, Comparison, Outcome, and Time to achieve the outcome) statement. In this assignment, you will formalize your PICOT and research process.


Use the GCU Library to perform a search for peer-reviewed research articles. Find five peer-reviewed primary source translational research articles.

In a paper of 1,250-1,500 words, synthesize the research into a literature review. The literature review should provide an overview for the reader that illustrates the research related to your particular PICOT. Include the following:

  1. Introduction: Describe the clinical issue or problem you are addressing.
  2. Methods: Describe the criteria you used in choosing your articles
  3. Synthesize the Literature: Part A: Discuss the main components of each article (subjects, methods, key findings) and provide rationale for how this supports your PICOT; Part B: Compare and contrast the articles: Discuss limitations, controversies, and similarities/differences of the studies.
  4. Areas of Further Study: Analyze the evidence presented in your articles to identify what is known, unknown, and requires further study.

You are required to cite 7 to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

Prepare this assignment according to the guidelines found in the APA Style Guide.

You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.


Read Chapters 8 and 9 in Population Health: Creating a Culture of Wellness.  URL:

Read Chapter 9 in Evidence-Based Practice in Nursing and Healthcare.  URL:

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    Benchmark Part A

    Your Name

    NUR 550 Translational and Population Health Management

    Grand Canyon University

    Write out the Date

    Benchmark Part A

    The following PICOT question will guide as the basis of proposed evidence-based practice project. For Hispanic adults residing in Arizona (P), how does introducing exercise protocol and cultural health nutrition (I) compare with utilization of universal protocols (C) in minimizing pervasiveness of Type 2 Diabetes (O) in 10 months (T).

    Type 2 diabetes is directly linked with a person’s general health status and physicality. The prevalence of the disease has doubled in the state of Arizona over the recent past, with adults becoming the most affected people. Lifestyle is the primary cause of the disease, meaning the condition can be regulated since lifestyles can be modified. Hispanic Americans are among the most affected population in Arizona. Genes play an essential role in this disease. However, cultural implications related to foods also are more exceptional factors for the disease.

    Population Description

    Diabetes is ranked number seven leading causes of death in the state of Arizona. Several ethnic groups have been impacted by type 2 diabetes compared to Non-Hispanic white population. The total population of Hispanics in Arizona is 31.6%. Diabetes prevalence for Hispanics in the state stands at 11.2% compared to that of Non-Hispanic, which is 9.5% (“U.S. Census Bureau Quick Facts: Arizona,” n.d.). The Hispanics have been said to be at a higher risk of complications related to diabetes, which include vision loss and acute strokes. In identifying the existing health disparities between Hispanic and Non-Hispanic, differences in their social lives is an essential element to take into account. Hispanic are more concerned with family wellbeing, and their focus is on food. Hispanics are less active physically.

    Synthesis of Nursing Science, Determinants of Health, and Epidemiologic and Genetic Data

    There exist various reasons as to why a given population can be at a higher risk of disease than another. Assessing the Hispanic population genetically, biologically, behavior-wise, and their overall performance, they significantly contribute to their higher health risks when compared to Non-Hispanic. The social, economic status of Hispanic whites plays a vital role in their health. Their lower status in socioeconomic lives makes it difficult for them to secure better and quality foods and even seek better medical services (Morales et al., 2020). The high cost of gym registration and other physical activities for fitness are assumed because they entail individual costs and constraints of time.

    Genomics can be defined as the study of cell genes that present in organisms and the ways through which the genes interact with various environmental factors that impact growth and development (Morales et al., 2020). Genomics is essential in identifying health concerns in a specific population. Incorporation of genomics and genetics into the health sector has been crucial in facilitating understanding of human genetics and its relationship to the environment (Molster et al., 2018). Possession of this vital information helps understand population composition and how its relationship with the environment result in health issues.

    PICOT and Potential Solution

    For Hispanic adults residing in Arizona (P), how does introducing exercise protocol and cultural health nutrition (I) compare with utilization of universal protocols (C) in minimizing pervasiveness of Type 2 Diabetes (O) in 10 months (T).

    There exist several government policies and programs in place which aim at regulatingT2D. The programs heavily rely on exercises. An example of such a program is the Diabetes Prevention Program (DPP) and Diabetes Self-Management Education (DSME). The program has helped organizations learn better ways of living the right lifestyle, which can minimize the chances of suffering from diabetes (Contreras & Sandoval-Rosario, 2019). Although education has been helpful for Non-Hispanic whites, the same program cannot be used by Hispanics whited because they do not have all these resources.

    Taking into account cultural norms and incorporate them into the solutions will be advantageous. For instance, they are coming up with culturally inclusive nutrition education and creating recipes that the population should be following in their daily cooking. This sounds more practical than asking them to follow instructions like gyms, which they view as recreational activities that require funds.

    Offering solutions through which affordable healthcare can be attained is essential. A more significant population of Hispanics is not insured. This creates it difficult for members to seek medical services. Education to be offered should not only aim at educating the people but also offering free medical services like screening.

    Incorporate Health Policy and Goals

    Arizona Diabetes Coalition remains a primary resource that will bring change to the population. They are responsible for providing education, lobbying policies, and creating awareness among the members of the community. The plan is in line with health policies and goals. That is the reduction of diabetes deaths by 10%. The chances of program success are fueled by incorporating cultural strategies.


    In summary, the prevention efforts for diabetes need to take into account cultural elements and should be inclusive of all people regardless of their social-economic status. For changes to occur among the Hispanic, policy changes must be taken into account. The resources in place should be re-evaluated and redirected towards upholding health issues within the population. Making the resources available becomes advantageous and will facilitate making changes towards the current lifestyles. Translational Research and Population Health Management


    Contreras, O. A., & Sandoval-Rosario, M. Diabetes in Arizona: The 2018 Burden Report,

    Diabetes in Arizona: The 2018 Burden Report (n.d.). Retrieved from

    Molster, C., Bowman, F. L., Bilkey, G. A., Cho, A. S., Burns, B. L., Nowak, K. J., & Dawkins,

    H. J. (2018, August 15). The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future. Retrieved from

    Morales, J., Glantz, N., Larez, A., Bevier, W., Conneely, M., Fan, L., … Kerr, D. (2020).

    Understanding the impact of five major determinants of health (genetics, biology, behavior, psychology, society/environment) on type 2 diabetes in U.S. Hispanic/Latino families: Mil Familias – a cohort study. BMC Endocrine Disorders20(1). DOI: 10.1186/s12902-019-0483-z

    U.S. Census Bureau QuickFacts: Arizona. (n.d.). Retrieved from

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