Assignment: Lisinopril and Caution in Renal Impairment

Question:

Discuss about the Lisinopril And Caution In Renal Impairment.

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Sample Solution:

Lisinopril

Trade Name: Prinivil, Zestril

Therapeutic Class: angiotensin-converting enzyme (ACE) inhibitor

Mode Of Action: selectively suppresses rennin-angiotension-aldosterone system, inhibits angiotension-converting enzyme (ACE) and as a result prevents conversion of angiotension I to angiotemsion II (Gorenchtein, 2018).

Indications: hypertension, heart failure and reduction in mortality rate in acute myocardial infarction.

Route And Dosage For Adults: Initial dose: 10 mg oral once a day; Maintenance dose: 20 to 40 mg, oral, once a day, Maximum dose: 80 mg orally once a day

Cautions And Contraindications: caution in renal impairment, volume depletion, hypotension, elderly patients, …